Synthesis of Some New N1- [Substituted 1,3-Benzoxazin-2 4-Dione-3-YL]-3-Methyl-Pyrazol-5-Ones

M. B. Hogale and B. N. Pawar

Department of Chemistry, Shivaji University, Kolhapur-416 004 (India)

ABSTRACT:

Synthesis of N, -[ substituted 1,3-benzoxazin*2,4-dione-3-yl ]-3-methyl-pyrazol-5-ones Va-f have been reported. 6-Halogen substituted 1,3-benzoxazin-2, 4-diones (Ia-b) were prepared by the reaction of 5-halogen substituted salicylamide with ethyl chloroformate followed by the refluction with acetyl chloride. These when condensed further with ethyl chloroformate, ethyl chloro acetate and chloroacetyl chloride formed corresponding Hp-substituted corbocthoxy derivatives lla-f. The reaction of Ila-f with hydrazine hydrate yielded hydrazides (IIIa-f). These when reao ted with acetoaceticester in dioxane formed compounds (IVa-f) followed by cyclization in refluxing O-dichlorobenzene yielded Ni-substituted pyrazoles (Va-f). The structures of these compounds were confirmed by IR, NMR and elemental analysis.

KEYWORDS:

6-Halogen; Substituted;

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Copy the following to cite this article: Hogale M. B Pawar B. N. Synthesis of Some New N1- [Substituted 1,3-Benzoxazin-2 4-Dione-3-YL]-3-Methyl-Pyrazol-5-Ones. Orient J Chem 1989;5(1).

Copy the following to cite this URL: Hogale M. B Pawar B. N. Synthesis of Some New N1- [Substituted 1,3-Benzoxazin-2 4-Dione-3-YL]-3-Methyl-Pyrazol-5-Ones. Orient J Chem 1989;5(1). Available from: http://www.orientjchem.org/?p=41346