Synthesis of Some Biologically Active 2-(N-Protected or Free Aminoacyl) Amino-6-Chlorobenzothiazole Derivatives

S. A. Abdel-Ghaffar, A. F. El-Haddad, Y. A. Abbas and J A. M. El-Naggar

Chemistry Department, Faculty of Science, Al-Azhar University, Naur-City, Cairo. (Egypt

ABSTRACT:

The synthesis of a series of 2-(N-Tos-or N- Pht-aminoacyl or free aminoacyl or N-Tos-or N- Pht-dipeptidyl) amino - 6-chIorobenzothiazole derivatives (II-XX) is described. Eight of various substituted 2-(N-Tos- or N-Pht- aminoacyl or free aminoacyl or dipeptidyl) amino-4-chlorobenzothiazole derivatives were found to possess specific antimicrobial activities toward different microorganisms

KEYWORDS:

Biologically; Amino-6-Chlorobenzothiazole

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Copy the following to cite this article: Abdel-Ghaffar S. A, El-Haddad A. F. Abbas Y. A. El-Naggar J. S. M. Synthesis of Some Biologically Active 2-(N-Protected Or Free Aminoacyl) Amino-6-Chlorobenzothiazole Derivatives. Orient J Chem 1989;5(1).

Copy the following to cite this URL: Abdel-Ghaffar S. A, El-Haddad A. F. Abbas Y. A. El-Naggar J. S. M. Synthesis of Some Biologically Active 2-(N-Protected Or Free Aminoacyl) Amino-6-Chlorobenzothiazole Derivatives. Orient J Chem 1989;5(1). Available from: http://www.orientjchem.org/?p=41358