Synthesis of New Heterocyclic Di Bromo Chalcone and Quinoxaline Compounds and Their Antibacterial Activity


K. H. Mehta and K. R. Desai
Department of Chemistry, South Gujarat University, Surat-395 007 (India)

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ABSTRACT:

Dibromo chalcohnes were prepared by the reaction of chalcone with bromine by using glacial acetic acid and Quinoxalines were prepared by the reaction of dibromo chalcone with benzene-1,2-diamine in presence of concentrated H2SO4 by using ethanol. The intermediate chalcone were synthesized by the reaction of 4-methoxy acetophenone with various aldehydes. The structures of the compounds have been confirmed by elemented analysis and spectral analysis. The antibacterial activity of the compounds have been screened.

KEYWORDS:

Heterocyclic chalcones; Quinoxaline compounds; Antibacterial activity


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