Synthesis of substituted-4-oxo-1, 4-dihydro-3-[1-oxo-2-hydrazino-3-{p-toluenesulfon}]quinoline Derivatives and their Biological Activity Against Bacterial Infections

N. Srivatava and A. Kumar

Department of Applied Chemistry, Faculty of Engineering and Technology, M. J. P. Rohilkhand University, Bareilly - 243 006, India.

Corresponding Author E-mail: drnimjpru@rediffmail.com

DOI : http://dx.doi.org/10.13005/ojc/290216

ABSTRACT:

We have synthesized a series of quinolone and fluoroquinolones derivatives substituted with p-tosyl group. All these compounds were screened as antibacterial and datas were compared with reference marketed drug viz.; Ciprofloxacin & Norfloxacin.

KEYWORDS:

Fluoroquinolones; hydrazine; p-tosyl and antibacterial

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Copy the following to cite this article: Srivatava N, Kumar A. Synthesis of substituted-4-oxo-1, 4-dihydro-3-[1-oxo-2-hydrazino-3-{p-toluenesulfon}]quinoline Derivatives and their Biological Activity Against Bacterial Infections. Orient J Chem 2013;29(2).

Copy the following to cite this URL: Srivatava N, Kumar A. Synthesis of substituted-4-oxo-1, 4-dihydro-3-[1-oxo-2-hydrazino-3-{p-toluenesulfon}]quinoline Derivatives and their Biological Activity Against Bacterial Infections. Orient J Chem 2013;29(2). Available from: http://www.orientjchem.org/?p=22142