Synthesis and Antimicrobial Assay of Some Ketoanils and their Thiazolidinones

Geeta Raghav, Sanidhya Upadhyay and R. K. Upadhyay*

Department of Chemistry, N. R. E. C. Collage, Khurja, India.

Corresponding Author E-mail: rkupadhyay14@gmail.com

DOI : http://dx.doi.org/10.13005/ojc/290235

ABSTRACT:

Nine kitoanils obtained by condensation of primary amines with thiophene glyoxal were used as precursors for the synthesis of thiazolidinones by their cyclocondensation with thioglycolic acid. The chemical structures of the synthesized compounds were confirmed by elemental analysis, molecular weight determination, IR and 1H NMR spectral measurements. Antibacterial and antifungal properties were studied in vitro against four bacteria and two fungi by using ampicillin and grislofulvin reference drugs respectively.

KEYWORDS:

Kitoanils; Thiophene glyoxal; Antibacterial and antifungal

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Copy the following to cite this article: Raghav G, Upadhyay S, Upadhyay R. K. Synthesis and Antimicrobial Assay of Some Ketoanils and their Thiazolidinones. Orient J Chem 2013;29(2).

Copy the following to cite this URL: Raghav G, Upadhyay S, Upadhyay R. K. Synthesis and Antimicrobial Assay of Some Ketoanils and their Thiazolidinones. Orient J Chem 2013;29(2). Available from: http://www.orientjchem.org/?p=22197