A Convenient Synthesis and Antibacterial Evaluation of Some Novel 4-Oxo-Thiazolidines

Anjani Solankee, Sejal Solankee, and Ghanshyam Patel

Department of Chemsitry, B. K. M. Science College, Valsad - 396 001 India.

ABSTRACT:

A new series of 4-oxo-thiazolidines (3a-e) have been prepared by cycloconndensation of hydrazones (2a-e) and mercapto acetic acid. Hydrazones (2a-e) have been synthesized by reaction between 5-bromofuran-2-carbohydrazide (1) with different aromatic aldehydes. The constitutions of newly synthesized compounds have been established on the basis of elemental analysis, IR and ¹H NMR spectral data. All the synthesized compounds have been evaluated for their antibacterial activity.

KEYWORDS:

Hydrazones; 4-oxo-thiazolidines; mercapto acetic acid; spectral data; antibacterial activity

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Copy the following to cite this article: Solankee A, Solankee S, Patel G. A Convenient Synthesis and Antibacterial Evaluation of Some Novel 4-Oxo-Thiazolidines. Orient J Chem 2008;24(1).

Copy the following to cite this URL: Solankee A, Solankee S, Patel G. A Convenient Synthesis and Antibacterial Evaluation of Some Novel 4-Oxo-Thiazolidines. Orient J Chem 2008;24(1). Available from: http://www.orientjchem.org/?p=23311