Synthesis and Screening of Some Heterocyclic Compounds for Their Antibacterial Activity With Special Reference to Benzamides Derivatives

Uttam M. Yadav¹, V. G. Bhawe¹, Rajesh C. Patil² and R. D. Pandit

¹Department of Chemistry, Bhavan’s College, Andheri, Mumbai - 400 058 (India) ²Department of Microbiology, Bhavan’s College, Andheri, Mumbai - 400 058 (India)

Three benzamide derivatives were synthesized. The structures of these compounds have been established on the basis of elemental analyses and NMR spectral data. These compounds have also been tested for their antibacterial activity against gram-positive (Staphylococcus aureus and Micrococcus lutea) and gram-negative (Escherichia coli and Klebsiella pneumoniae) bacteria and compared with standard drug Sulfaethidole.

heterocyclic compounds; Synthesis; Antibacterial activity