Synthesis and Antimicrobial Activity of 2-Hydroxy-4-Methyl-5-Chloro Acetophenone/Propiophenone Hydrazones and their Metal Complexes

K. T. Joshi; A. M. Pancholi; R. K. Rai; J. Franco

Article | Open Access

Synthesis and Antimicrobial Activity of 2-Hydroxy-4-Methyl-5-Chloro Acetophenone/Propiophenone Hydrazones and their Metal Complexes

K. T. Joshi1, A. M. Pancholi², R. K. Rai¹* and J. Franco²

¹Department of Chemistry, Navjivan Science College, Dahod - 389 151 India. ²Department of Chemistry, Bhavan's R .A. College of Science, Ahmedabad India.

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ABSTRACT:

2-Hydroxy-4-methyl -5-chloro acetophenone hydrazone, 2-hydroxy-4-methyl-5-chloro propiophenone hydrazone and their metal chelates have been synthesized and characterized by Elemental, IR and NMR study and screened for the antimicrobial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Pseudomonas fluorescens and Aspergillus niger.

KEYWORDS:

2-Hydroxy-4-Methyl-5-Chloro; Staphylococcus; Pseudomonas; Aspergillus