Volume 39, Number 5
Volume 39, Number 5
A Practical Approach for Solubility Enhancement of Leflunomide
Introduction Leflunomide is 5- Methyl- N- [4-(trifluoromethyl)phenyl]- 4- isoxazole carboxamide, structure shows in figure 1.1 It is a drug used to treat rheumatoid arthritis.2 Leflunomide is practically insoluble in water. Poorly soluble drugs can...
Read MoreSynthesis and Characterization of 6-Amino Caproic Acid Tkp-Based Resin for Wastewater Treatment
Introduction Water is the prime resource on land because all living things must survive. One of the basic needs for all life on earth is access to clean drinking water. But there are many...
Read MoreQuantitative Mineralogical Analysis and Study of Morphology and Thermal Characteristics of Rock Samples of Dudhi Nala and Bokaro River.
Introduction Damodar Valley Basin, an important storehouse of indian coal, is part of the Gondwana Systems. The beds of Talchir formation are well exposed in the western part of the Bokaro basin, ( Dudhi...
Read MoreSynthesis of Schiff bases Derivatives of 1,3-oxazepine and Evaluation of Antioxidant Action In vitro
Introduction Oxazepine are seven membered heterocyclic structures with one nitrogen and one oxygen replacing the carbon atom at various positions 1. . Three isomeric forms of oxazepine have been known (Figure 1). Figure 1:...
Read MoreElegant Explorations of Ionic Liquids in the Expeditious Synthesis of Fe3O4 Nanoparticles
Introduction Transition metal nanoparticles are critical for a wide range of potential applications in science and industry, including sensors and catalysts.1-5 Several physical and chemical approaches were used to form metal oxide nanoparticles of...
Read MoreComparative Phytochemical Analysis of Kanakasava, Kanakasava Distillate, and Kanakasava Nebulizer Solution Using Gas Chromatography-Mass Spectrometry (GC-MS)
Introduction Chronic respiratory disorders, which can affect both adults and children, are becoming more and more prevalent worldwide. According to WHO, an estimated 400 million individuals worldwide suffer from asthma and chronic obstructive pulmonary...
Read MoreEco-friendly Synthesis of Strontium Oxide Nanoparticles using Solanum nigrum Leaf Extract: Characterization and Antibacterial Potential
Introduction Biomedical research, food processing, electrochemical systems, beauty and personal care, pharmaceutical development, catalytic reactions, sensor technology and other nanotechnology fields have advanced greatly in the past decade. These advances pollute the environment 1...
Read MoreSynthesis, Characterization and Evaluation of Antimicrobial Properties of Novel Oxazine and Thiazine Compounds Derived from Chalcones
Introduction Oxazines and Thiazines, two classes of organic compounds, exhibit a diverse array of biological activities, making them subjects of significant interest in the field of chemical and pharmaceutical research. In this comprehensive report,...
Read MoreThe Analysis of Pyrostegia Venusta Flower Mediated Dye as Sensitizer for TiO2 Based Dye Sensitized Solar Cells
Introduction After Gratzel and others, first invented the DSSC in 1991, the scientific community became very interested in the DSSC because of its low costs of production and its ecological advantage. 1. The DSSCs...
Read MoreDFT study of Lithium, Sodium and Potassium salts of Amino Acids; Global Reactivity Descriptors, Optimized parameters and Hydration Free Energy
Introduction Major greenhouse gas carbon dioxide (CO2) is accountable for the global warming that has been observed over the past few decades, as well as for the worries about relatedclimate change and its potential...
Read MorePhytochemical Screening and In-vitro Antibacterial Activity Evaluation of Lantana Camara Linn. Leaf Extract
Introduction Nowadays the rate of infections is increasing drastically due to various climatic conditions. All these infections are due to different microorganisms such as bacteria, viruses, fungi, parasites, etc. To overcome these microbial infections,...
Read MoreSynthesis and Biofunctional Evaluation of Novel Isoxazole, C-Nucleoside, and Thioxopyrimidine Derivatives
Introduction Organic chemistry’s thiopyrimidines constitute an intriguing subject with a wide range of practical and research applications. They make adaptable building blocks for the synthesis of diverse compounds with specific features because of their...
Read MoreQuantification of Telmisartan and Azelnidipine Combination in using Liquid Chromatography: Stability Studies
Introduction Telmisartan (TTN) is chemically approved and the molecular formula is C33H30N4O2 and the molecular weight is 514.62. TTN is acting as receptor inhibitor for angiotensin II1,2. It consists of very broad area of...
Read MoreInvestigation of Linagliptin – Human Serum Albumin Complex formation using Spectroscopic Analysis and Molecular Docking
Introduction Plasma protein binding (PPB) is a crucial factor that significantly affects the pharmacokinetics of a chemical substance 1. PPB also affects medication stability, toxicity, and pharmacological effects 2. Early in the drug development...
Read MoreSynthesis of CeO2-GO Nano Composite and its Impact on SOD1 Protein Through Computation Study: Molecular Docking
Introduction Nanoparticle development has branched out into a wide spectrum of clinical uses in the last few decades. Nanoparticles have been intended to overcome the limits of free treatments and to transportation biological barriers...
Read MoreNanocellulose from Agricultural Waste – A Concise Insight into Extraction and Applications
Introduction Agricultural production is forecasted to increase further to provide food to the burgeoning world’s population as well as to meet the industrial needs and animal food requirements1. The manufacture of biofuels had a...
Read MoreVisualizing Structure Models and Patterson Densities in four WS2 Polymorphs: Metastable (1T’, 4M) and Stable (2H, 3R) Phases
Introduction The fascinating phase-dependent physiochemistry of transition metal disulfides (TMDSs) in particular MS2 (M = Ti, Zr, V, Mo, W, Fe, Re) make them as active materials for innovative applications and have enormously been...
Read MoreDesign of Novel Thiohydantoin Derivatives and Exploration their Physico-Chemical Parameters
Introduction 2-Thiohydantoin is an important class of compounds within chemistry. It is a sulphur derivative of hydantoin which is obtained by replacing the oxygen atom of carbonyl group by sulphur. Thiohydantoin is a intermediate...
Read MorePhotocatalytic Degradation of Azo Dyes by Zinc Oxide Nanoparticles Fabricated using Aqueous Flower Extract of Cassia alata
Introduction Water is an inevitable resource for the sustenance of all life forms on Earth. The swift industrial growth in developing countries emanates fromwater pollution due to organic and inorganic pollutants. Dyes are one...
Read MoreRheology of Almond (Prunus amygdalus) Oil used as Biodegradable Lubricant
Introduction Almond (Prunus amygdalus) oil is recommended for those for whom other treatments to remedy hair loss problems have not worked. Massaging the scalp with almond oil twice a week has a remarkable effect...
Read MoreSearch for New Inhibitors of Human Aromatase Enzyme (Cyp450) from Bioactive Compounds of Citrus species
Introduction Aromatase (gene CYP19) belongs to the cytochrome P450 enzyme family that synthesizes oestrogens from androgens. This gene expression was regulated differently in various tissues including breast, skin, adipose tissue and brain and so...
Read MoreSynthesis, Characterization, Molecular Docking and Anti- Anxiety Evaluation of Some Novel Phenothiazine Derivatives
Introduction Present scenario of the world reveals that the anxiety is a communal human emotion that includes behavioral, affective, and cognitive reactions to perceived threat. Occasionally, anxiety encourages a proactive and receptive reaction to...
Read MorePreparation of Gbsa (Guargum 1-Butane Sulphonic Acid) Resin and Study of their Physicochemical Characterization and Use for Removal of Toxic Metal from Effluents
Introduction Heavy metal ions, including ferrous, copper, zinc, lead, and others, have been found in the effluent from the mining, tannery, electroplating, battery, and steel sectors. When they exceed tolerance thresholds, heavy metal ions...
Read MoreStudy on Solution Behavior of Green Gemini-Conventional Mixed Systems and their Solubilization Capability Towards Phenanthrene
Introduction Surfactants are surface active agents; they contain both hydrophilic as well as hydrophobic parts, therefore they are amphiphilic in nature. Depending upon the charge present on the polar head, they are categorized as Ionic...
Read MoreEffect of Frying and Reheating Processes on the Fatty Acids and Antioxidants of Commonly Used Cooking Oils in the Arabian Region: A Comparative Study
Introduction The use of fat or oil for frying is one of the most popular ways to prepare meals since deep-fried foods are a cornerstone of the diet and are readily available from sellers...
Read MoreStudy of Corrosion Resistant Property of Benzoxazine Synthesised from Euginol with N-Butylamine and Copolymerised with Polyurethane on Mild Steel
Introduction Corrosion means degradation of metal or alloys by direct interaction with the environment. Mild steel can widely use in large number of applications, marine application, pipelines which are highly used to transport oils...
Read MoreTunable Paramagnetism in Mn co-doped N:CdS Composite Nanoparticles
Introduction Nanocrystalline CdS is well known as an easy-tunable, wide-direct-band gap semiconductor. It allows the doping of a wide variety of elements, ranging from s-block to f-block, as dopants. Depending on the nature of...
Read MoreRecent Monitoring of Ground Water Quality in and Around Industrial Area of Vellore City at Two Different Monsoon Periods, South India
Introduction Different processes, including organic matter degradation, rock-water interactions, aerobic respiration, iron reduction, mineral dissolution, weathering, industrial discharge effluents, and mixing of fresh and salt water, have been connected to variations in groundwater quality...
Read MoreCissus quadrangularis is a Potential Anticancer Herb – A Review
Introduction The perennial species Cissus quadrangularis (CQ) is a member of the Vitaceae family. It is a common climber that can be found in the majority of India’s tropical regions. Cissus quadrangularis is a...
Read MoreSynthesis and Spectroscopy Characterizations of Some New Bis 1,3-thiazolidin-4-ones Derived from 4-hydroxybenzaldehyde Substrate
Introduction Heterocyclic compounds have been classified as one of the most significant classes of organic molecules as a result of their use in industrial and pharmaceutical applications.1-13 The most significant of them are thiozolidinones (Scheme 1),...
Read MoreDevelopment of a Multi Residue Method for the Quantification of 45 Pesticides Using Gc-Ms/Ms and Study of Peeling Effect on Pesticide Residues in Citrus Fruits
Introduction The Rutaceae family, which includes citrus fruits, is the most well-known and commonly cultivated fruit family in the world, with an annual production of 158 million metric tonnes 1. China is the world’s...
Read MoreBeneficiation of Coal with Biochemical Method and Effect of Treated Coal on Boiler Efficiency In Power Generatation.
Introduction Even after the bulk addition of renewable energy in the Indian energy sector, the contribution of energy generation from fossil fuels is very significant i.e., around 58% of the energy requirements are being...
Read MoreA Comprehensive Review on the Techniques and Indexes Used for the Analysis of Fluorosis in Humans and Cattle
Introduction The health of the population of an area is significantly determined by the quality of water consumed. Groundwater is the most crucial water source for any nation and has a critical role in...
Read MoreSynthesis and Cyclooxygenase-2 Inhibitory Activity Evaluation of Some Pyridazine Derivatives
Introduction Cyclooxygenase-2 (COX-2), an inducible enzyme, is produced during the inflammation of the body cells1. The untreated inflammation may progress to many diseases, including disability-causing diseases (different types of arthritis and Alzheimer’s disease), cancer,...
Read MoreDesign, Synthesis and Anticancer Properties of Novel Hydrazino-Fused Pyrimidines
Introduction Protein kinases have emerged as a possible therapeutic targets, with nearly 30 distinct kinase targets being developed for the phase-I trials1. The cell cycle regulation and proliferation mainly depend on cyclin-dependent kinases (CDKs)....
Read MoreExploring the Expanding Frontiers: The Promising Role of Supramolecules in Advancing Cancer and Infectious Disease Therapy
Introduction Cancer and bacterial infections remain significant public health challenges worldwide. Cancer is a complicated and diverse illness defined by uncontrolled cell growth and proliferation that can infiltrate and spread to other region of...
Read MoreThickening Performance Evaluation and Molecular Dynamics Simulation on Hydrophobic Associated Polymer in Acid Circumstances
Introduction The ever-increasing exploration on oil and gas reservoir brings abundant fossil fuels and resources. The oil reservoir is mainly consisted of volcanic rock reservoir, clastic rock reservoir and carbonate reservoir. Among these reservoirs,...
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