ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Volume 33, Number 2

Volume 33, Number 2

Modeling of IC50 (5-LOX and COX) Activity of Phenol Derivatives Against Leukemia Cells

Introduction In the present study we shall use a series of phenol derivatives for QSAR & QSPR studies. Phenol’s derivatives like Bobel-241 (2,4,6-Triiodophenol or AM-24) induce caspase-independent mitochondrial cell death in leukemia cells inhibited...

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Study of Ambient Air Quality Trends and Analysis of Contributing Factors in Bengaluru, India

Introduction Accumulation of certain substances in the air which adversely affect the well being of human, plant, animals and the environment causes air pollution. These chemicals are added in many ways, for example pesticides,...

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Application of the Spark Discharge Generator for Solvent-free Aerosol Jet Printing

Introduction Aerosol jet printing is a promising method for fabrication of printed electronics goods, such as sensors1,2, solid oxide-fuel cells3, solar cells4 and organic LEDs5. The conventional approach of aerosol jet printing is based...

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Calculation of Spin Orbit Coupling of Tungsten (III) Complexes: A DFT Application

Introduction Unlike the 1st transition series metal ion complexes, there had, hardly, been any study done on the calculation of Spin Orbit Coupling (λcomplex) of the corresponding complexes of 2nd and 3rd transition series....

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Synthesis and Characterization of Various Alkyl, Aryl and Hetero Aryl Substituted Hydrazines and Study of their Biological Activity

Introduction Among the nitrogen-nitrogen bond containing chemical the hydrazines are well-known for their diverse biological activity and as therapeutic agents in medicines. Many hydrazine derivatives are known to exhibit significant biological activity and several...

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Synthesis and Applications of Nano Metallic Particles Anchored on A Novel Polymeric Resin

Introduction Since the introduction solid phase synthesis of functional polymers have found extensive applications in organic synthesis [1].They have been used as reagents, catalysts, in chromatography, in medicine and as substrate carriers [2]. One...

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Bicl3: A Versatile Catalyst for the Tetrahydropyranylation and Depyranylation of 1°,2°,3°,Allylic,Benzylic Alcohols, and Symmetric Diols

Introduction While doing multi stage organic synthesis, the protection and deprotection of alcohols by various reagents is a most common event. The  most common protected forms of alcohols are  ethers and esters, where as...

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Remediation of Nickel Ion from Soil and Water Using Nano Particles of Zero-Valent Iron (nZVI)

Introduction The management of nickel and other pollutant in soil and water is a major current environmental issue. Nickel is naturally occurring in surface water and soil but some actives like industrialization, urbanization, use...

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Synthesis and Studies of Properties of Crosslinkable Copolymers Based on Methyl Methacrylate

Introduction Copolymerization is one of the important technique adopted to achieve systematic changes in the properties of commercially important polymers1. Acrylates and methacrylates are highly versatile building blocks that readily polymerize or copolymerize with...

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Differential Pulse Voltammetry Technique for the Determination of Imipramine, Dopamine and Norepinephrine using A Hydroquinone Derivative Multi-Wall Carbon Nano-Tube Carbon Paste Electrode

Introduction Imipramine (IM), the first tricyclic antidepressant that was introduced in last decade of 1950s by Ciba, is used for the treatment of enuresis and deep depression. The powerful antidepressant properties of imipramine have...

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Antimicrobial Activities of Extracts of Some Species of Mangrove Plants and A New Compound Isolated Towards Some Selected Strains

Introduction The recent investigations are concentrating on the bio-screening of natural products have revived due to the paucity of safe antimicrobial drugs, anti-reverse transcriptase, anti-HIV and the perilous upsurge of new and re-emerging infectious...

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Study on Ion Exchange Behavior of Nuclear Grade Resin Auchliteara 9366 Chemically Degraded in Hydrogen Peroxide Medium

Introduction The AuchliteARA-9366 was a strong base nuclear grade anion exchange resin having cross linked polystyrene matrix. Strongly basic anion exchange resins can be useful for 1waste water treatment in large number of food...

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Structure and Tribological Properties of Self – Reinforced Composite Materials Based on UHMWPE and Oxides of Titanium, Zirconium and Hafnium

Introduction Interest in the existing and developing polymer matrix components (PC) is caused by the ability to control their physical-mechanical and tribological properties with respect to working conditions of friction units of various machines...

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Development and Validation of RP-HPLC Method for Quantification of Berberine in Ethanol Fraction of Methanol Extract and Developed Formulation of Tinospora Cordifolia

Introduction T. cordifolia  belonging to Menispermaceae family, is also known as Guduchi, Amrita and Giloy. It showes a wide range of pharmacological effects such as general tonic, analgesic, hypoglycaemic and immunomodulatory agent.1-8. It contains...

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Identification of Flavonoids in Iraqi Date Palm Pollen By HPLC

Introduction Date Palm Pollen (Phoenix dactylifera, L.)-DPP is a fine, powder-like material produced by flowering plants and gathered by bees (1),it is very important  causing of human respiratory allergic disorders, involving the production of...

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Adsorption Study of Pb(II), Cd(II), Cu(II) and Cr(III) Ions in Aqueous Medium using C-4-Hydroxy-3-Methoxyphenylcalix[4]Resorcinarene Dodecaacetate

Introduction Heavy metal contamination in water is a serious problem, particularly in the health and environmental aspects. It occurs since many industries discharge their waste without any proper treatment. Most of the heavy metal...

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Synthesis and Anti-Inflammatory Activity of Hydrazones Bearing Biphenyl Moiety and Vanillin Based Hybrids

Introduction The advancement of novel chemotherapeutic agent is an imperative and demanding task for the medicinal chemist. Many research programs are aimed towards design and synthesis of new drugs. Research on new substances possessing...

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Copper(II) Carboxylate Containing Paddle Wheel Structure: Synthesis and Crystal Structure

Introduction Generally, most copper(II) carboxylates display the dinuclear paddle-wheel cage structure which consists of two copper centers bridged by four carboxylate molecules and each copper(II)  is attached to a neutral ligand . The dimeric...

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Phytochemical Screening of Caralluma Lasiantha: Isolation of C21 Pregnane Steroid

Introduction In ancient system of medicine like ayurveda , unani and in folkaric medicine, several plants belongs to asclepiadaceae are proved to be helpful in healing of disorders. Asclepiadaceae family includes 200 genera and...

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Study of Correlation Between the Atomic Numbers and the Atomic Weights of Elements in the Periodic Table With Sierpinski Triangle Fractals

Introduction In 1975 Benoit Mandelbrot introduced a new branch of geometry known as fractal geometry to find order in chaotic shapes. In fact, fractal geometries describe the fractals which have complex geometric structures in...

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Determination of Aniline Blue dye by flow Injection Analysis With Home Made Valve

Introduction Flow injection analysis (FIA) is one of recent techniques are established by Ruzicka an Hansen in 1975 at Denmark and Stewart in USA that is the first generation (1). The second generation of...

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Corrosion Rate Monitoring of Mild Steel in underground Soil at Different Depths using Electrical Resistance (ER) Probe Technique

Introduction The corrosion of metallic structures buried in soils or in contact with soils has long been a serious engineering and economic problem. Underground metal structures are usually expected to have a long durability...

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Synthes and Green Metric Evaluation of 2-(Chloromethyl)-3-Methyl-4-(Methylsulfonyl)Pyridine

Introduction A prominent class of drugs that bring out distinctive and enduring pharmacological effect by reducing the gastric acid production are the Proton pump inhibitors (PPIs). Due to their outstanding efficacy and safety, these...

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Stability Indicating RP-UPLC-PDA Method Development, Validation of Multi Drug Combination of Emtricitabine, Tenofovir Alafenamide and Rilpivirine in Bulk Drug and its Tablet Formulation

Introduction Emtricitabine, Rilpivirine, and Tenofovir Alafenamide combination is used in the treatment of HIV-1 as initial therapy as a part of anti retroviral therapy1-3 .This combination was approved in March 2016 by US-FDA. Literature survey...

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Strength of Material Hap-Borosilicate and their Sintering Behavior

Introduction Hydroxyapatite is a material that can be used as a biomedical material. It can also be used as a material implant1. This material has similarities with human bones2. Hydroxyapatite can be obtained by...

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Adsorption of Benzene Butyl Phthalate with Mullti-walled Carbon Nanotubes/Ag nanoparticles and its Applications

Introduction Phthalate acid ester (PAEs), generally known as phthalates, is used in many usable and household products, such as industrial plastics, polyvinyl chloride (PVC) products and personal care products. PAEs with high molecular weight...

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Biosynthesis and Characterization of Zinc Sulphide Nanoparticles using Leaf Extracts of Tridaxprocumbens

Introduction From last decades, nanoparticles have been received too much attention due to its unique properties like high surface area, magnetic, thermal, mechanical, electronic and enhanced catalytic properties. The nanotechnology has been remarkable development...

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Determination of the Percentages of Some Fatty Acids Present in A Sample of Olea Oil Traded in Sudanese Markets Present

Introduction Olea oil is a fat obtained from the olive (the fruit of Olea europaea; family Oleaceae), a traditional tree crop of the Mediterranean Basin. The oil is produced by pressing whole olives. It...

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Synthesis of Fused-oxazines from Cyclic Ketoximes via α-Nitrosoalkenes

Introduction 1,2-Oxazine and their fused counterparts received interest in these years due to their diverse synthetic and pharmacological importance. 1,2-Oxazine derivatives are useful synthetic building blocks in heterocyclic chemistry. In our preceding report1, we...

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Environment for the Formation of Shale oil and Gas Accumulations in Low-Permeability Sequences of the Maikop Series, Fore-Caucasus.

Introduction The Khadum and Batalpashin sediments of the Maikop series, which include hydrocarbon (HC) accumulations in the Fore-Caucasus, are represented both by conventional and low permeability shale reservoirs. The petrology calls oil and gas...

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Preparation and Characterization of Solid Dispersion Telmisartan – Hydroxypropyl Methyl Cellulose (HPMC) E5 LV by Co-Grinding Method

Introduction  Telmisartan (TMS), an antihypertensive drug, belongs to angiotensin receptor blockers (ARBs) which act by inhibiting receptor stimulation of angiotensin II type 1 (AT1) without affecting other related receptors in cardiovascular1. TMS is classified...

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Synthesis, Characterization and Biological Activity of Novel Salt/Molecular Salts of Tinidazole

Introduction An infection that is caused by Entamoeba histolytica, in the large intestine, is named as Amoebiasis, which resides mainly in the intra-intestinal lumen. Targeting the drug to colon is an efficient way of...

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Kinetic Analysis of Thermal and Hydrolytic Decomposition of Spiroborate Ester of Curcumin with Salicylic Acid

Introduction Curcuma longa commonly called as turmeric is a widely used spice, food coloring agent and preservative agent in Asian countries.1 Curcumin is the bioactive component present in turmeric and has many biological applications.2...

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The Reactivity of the Donor-Acceptor Complex of Titanium Tetrachloride and N-Methylformanilide in Solvothermal Processes of Titanium Dioxide Formation

Introduction Titanium dioxide and various oxide systems containing titanium dioxide attract interest due to the presence of a catalytic, as well as signified photocatalytic activity. The possibilities of obtaining titanium dioxide and oxide systems...

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Photochemical Method of Applying Gold films on the Dielectric Surfaces

Introduction Due to several features of the physical-chemical properties a gold coating of dielectrics is widely used in engineering. These features include: corrosion resistance, high electrical and thermal conductivity, low and stable contact resistance...

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Synthesis and Characterization of Carbon foam from Gelatin (Cfg)

Introduction Carbon foam as new material that has good conductivity, high thermal and mechanical stability which is attracting much research attention1. The application of carbon foam in wide range field has been reported as...

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Synthesis of Benzo[G]Quinoxaline-5,10-Dione Based Pyridine Derivatives and their Antimycobacterial Activity

Introduction Quinoxaline and pyridine derivatives constitute the important part of various antibiotics viz. hinomycin, levomycin and actinoleutin that inhibit the growth various bacteria and are found to be cytotoxic against various transplantable tumours1-7. Quinoxaline...

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Ag/Tio2 Nano Thin Films Catalyzed Efficient Synthesis of 6-Amino-4-Aryl-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitriles at Green Conditions

Introduction Titanium dioxide is the most popular and efficient semiconductor photo catalyzer due to its strong oxidative ability of photo generated electron-hole pairs on its surface 1-2.  This efficient photo catalysis has been studied...

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Optical Absorption and Scattering Propertiesof the Active Layer of Perovskite Solar Cells Incorporated Silver Nanoparticles

Introduction The metal nanoparticles (NPs) such as gold (Au), silver (Ag) and copper (Cu)which possess a negative real and small positive imaginary dielectric constant in thin films or nanostructures are potential candidates in many...

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Synthesis, Characterization and Structural Study of New Ethyl Thiourea Compounds and the Preliminary Naked-Eye Sensors for Mercury (Hg) and Argentum (Ag) Metal Ions

Introduction Thiourea is similar to urea compound except the oxygen atom in urea is replaced by the presence of sulphur atom in thiourea compound.1 The chemical properties of both compounds are different because of...

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Comparative Study of Decomposition Adsorption of Sarin on Znn on and Cdn on (n=1,4), by Theoretical Method

Introduction Chemical warfare agents (CWAs) have been used in the World Wars that to cause killing and injuring a large number of people [1]. The stable complexes of CWAs with acetylcholine esterase enzyme at...

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Evaluation of the Role of Cetyltrimethylammoniumbromide (CTAB) and Acetylenic Glycol (AG) Admixture on fly ash Based Geopolymer

Introduction Geopolymer has recently emerged as a greener binder material for sustainable construction [1]. It is well known for its excellent properties such as fire and acid resistance, high compressive strength, low shrinkage and...

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Synthesis, Characterization and Antibacterial Evaluation With Computational Study of new Schiff Bases Derived from 7-Hydroxy-4-Methyl Coumarin

Introduction Coumarins are important class of compounds, they demonstrate useful and different activities, often depending on the substituents they include, benzopyran moiety 1,2. Coumarins are natural compounds produced by various plant sources. Their structures...

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Surface Enhanced Raman Spectra and Theoretical Study of an Organophosphate Malathion

Introduction Wrong agricultural habits have caused an adverse effect to human health and environment because toxic and biologically harmful substances are used as insecticides [1].  Insecticides used to increase the yield in agriculture are...

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Theoretical Studies of Solvent Effect for Oxindole Derivatives using Polarizable Continuum Model

Introduction Oxindoles are useful building blocks for indole chemistry. Heterocyclic compounds containing 5 to 6 membered ring are important for their diverse biological activities1. The chemistry of oxazolidinone and its derivatives have received considerable...

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Use of Aqueous Extract of Pseuderanthemum acuminatissimum Radlk Leaves to Mediate the Synthesis of Gold Nanoparticles and Their Anti Eschericia coli Activity

Introduction Functionalized gold nanoparticles (AuNPs) have potential as antimicrobial materials to counter, for example, fungi and bacteria [1]. Increasing efforts have been dedicated to research in this field, especially in the development of metal...

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Synthesis and in Silico Analysis of Novel 1,2,4-Triazolylamides as Potential Antifungals

Introduction Complex II inhibitors play an important role in agrochemical fungicide research and have been known for more than 40 years [1]. The amide belongs to this group of inhibitors and has been known...

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Synthesis Characterization and Analytical Applications of Antimony(III) molybdoarsenate as a Cation–Exchanger and Selective for Pb(II) and Cu(II) Ions

Introduction Ion-exchange may be defined as reversible interchange of ions takes place between two phases is solid and liquid1. Ion-exchange technology is most important versatile technology in the field of separation science. These techniques...

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Experimental and Theoretical Study of the Substituted (Η6-Arene)Cr(CO)3 Complexes.

Introduction Arenechromiumtricarbonyl compounds have been explored extensively and are very versatile agents [1-9]. This compound has many applications ranging from organic synthesis, molecular switches, tunable molecular cables, optical information storage devices and nonlinear optical...

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Design, Synthesis, and Anti-Inflammatory Activity of Novel Quinazolines

Introduction Heterocyclic compounds form the basis of many pharmaceuticals, agrochemicals, and veterinary products. Among a wide variety of nitrogen heterocyclic moieties, quinazolinone possess a diverse biological activity profile. The pharmacodynamics versatility of quinazolin-4-one moiety...

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Spectral Characterization and Vibrational Assignments of Ethyl 4-(3-(2,3-Dihydrobenzofuran-5-Carboxamido)Phenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate by ab Initio Density Functional Method

Introduction Dihydropyrimidin-2-(1H)-ones plays a vital role in natural and synthetic organic chemistry. It have wide range of biological activities 1,2. Such as, anti-leishmanial3, anti-tuberculosis4, analgesic, anti-inflammatory5-7, antimicrobial8, antifungal9 anti-emetic10 and antitumor properties11.  The nonlinear...

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Preparation of a MWCNT-graphite Composite Based on Sol Gel Method for Dye Removal

Introduction Dyes are colored organic compounds that are applied to impart color to various substrates including paper, leather, fur, hair, drugs, cosmetics, wax, grease, plastics and textile materials [1]. Dyes used in the textile...

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NMR Shielding and S-NICS Investigation for Imipenem, Penicillin G, Ticarcillin, Ampicillin and Clavulanic Acid in Viewpoint of Bio-Nanotechnology

Introduction Antibiotics are molecules that stop or kill the growth of, microorganisms, including both bacteria and fungus. Antibiotic that block the growth of bacteria is called bacteriostatic” and antibiotic that kill bacteria is called...

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Synthesis of Star-Shaped ε-Caprolactone Oligomers for use as Plasticizers of Poly(L-Lactide) Bioplastic films

Introduction Poly(L-lactide) (PLA), one of the most important bioplastics, has attracted increasing attention as a candidate for use in many application fields, such as tissue scaffold, drug delivery systems, packaging films and so on,...

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Synthesis and Characterization of Zno-Ag Nanoparticles Supported on MCM-41 as Photocatalyst.

Introduction In textile industry, dyes are used as raw material, which generates 525,000 tons per month of waste water1; as example of dye used in the past is the Congo red, which was prohibited...

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Electrochemical Study on Corrosion Inhibition of Iron in Acidic Medium by Moringa Oleifera Extract

Introduction Used in a large number of applications mild steel is one of the   important metals. Corrosion is the result of the interaction between the metal and environments, leading to its destruction gradually, so...

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Composite Film of Chitosan Loaded Norfloxacin With Improved Flexibility and Antibacterial Activity for Wound Dressing Application

Introduction Chitosan (CH) is an attractive polymer to be considered for medical applications as they are biocompatible and biodegradable. It is a linear cationic polysaccharide, and one of the most abundant polysaccharides occurring in...

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Solvent-Free Synthesis of New Bis(Benzimidazole-2-Alkylthio) Polyethylene Oxides Starting from Dithiols

Introduction Poly(ethyleneoxide) PEO is a biocompatible eroding polymer available in a various molecules. PEO have recently received wide attention as sustained-release bioadhesive platform due to its safety, ease of processing and possibility to control...

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Synthesis and Characterization of Functionalized Se-Mcm-41 A New Drug Carrier Mesopore Composite

Introduction Mesostructured silica particles have many attractive features such as high pore volume, large surface area and narrow pore size and ease of functionalization [1, 2]. One of the most well known mesoporous molecular...

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Effect of Al13 Polycation Grafting on Apple Wastes Activated Carbon That Have A Porous Structure

Introduction Activated carbon is regarded as an oldest adsorbent known in air pollution control and wastewater treatment .nevertheless, the use of this adsorbent for depollution processes is considerably restricted because it is very costly...

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Synthesis of Tio2 and Sio2 Oxide Systems, Containing Nanoparticles of Palladium and Platinum

Introduction Materials based on titanium dioxide are well known thanks to the pronounced catalytic and photocatalytic properties [1-7]. Presence of metallic nanoparticles formed of platinum group metals in oxide systems based on titanium dioxide,...

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Mixed Ligand, Palladium(II) and Platinum(II) Complexes of Tertiary Diphosphines with S-1H Benzo[D] Imidazole-2-Yl Benzothioate

Introduction Benzimidazole is the heterocyclic aromatic organic compound1. This bicyclic ring system consist of benzene ring joined with 4- and 5- situation of imidazole ring, imidazole ring having non adjacent two nitrogen atoms2. 2-Mercaptobenzimidazole...

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Preparation of Vancomycin Hydrochloride Nanoparticles and Survey of the Factors Influence their Properties

Introduction Among the major challenges in pharmaceutical fields it is certainly relevant the issue concerning the improvement of permeability and absorption of drugs (1). Particle size is one of the factors most influencing the...

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Expeditious Synthesis and Spectroscopic Characterization of 2-Methyl-3-Substituted-Quinazolin-4(3H)-one Derivatives

Introduction Heterocyclic compounds form the basis for pharmaceutical industry especially in the synthesis of drugs1. Also, most marketed drugs constitute of common structural units of heterocyclic compounds which could also be useful in the...

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Investigation on Stability of Electroplated-Sulfurized CuInS2-based Photocathode Modified with an In2S3 Layer for H2 Evolution under Various pH Conditions

Introduction Hydrogen (H2) produced by photoelectrochemical (PEC) water splitting via direct use of sunlight irradiation is considered to be a holy grail to provide sustainable fuel that can support human life for many years...

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NMR (13C, 17O), IR and Raman Studies of Poly-Nuclear Carbonyls Transition Metal Carbonyls : A DFT Application

Introduction   We had  successfully applied DFT to study NMR parameters such as: Shielding Constants (σM ,σ 13C,σ 17O),Chemical Shifts (δ M, δ13C, δ17O),two diamagnetic and four paramagnetic contributing terms in the σ values...

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