Volume 29, Number 1

Synthesis, Characterization and Spectral Studies of Gold Complex With Gliclazide, an Oral Antidiabetic Allopathic Drug

Introduction Metal ion are required for many critical function in humans .Scarcity  of some metal ions can leads to disease1. Well – known  example  can  leads  to  pernicious anemia   resulting from  iron  deficiency;  growth ...

Reverse Microemulsions as A Novel Reaction Media

Introduction When water is mixed with an organic liquid immiscible with water and an amphiphile, generally a turbid milky emulsion is obtained which separates after some time into an aqueous and an organic phase....

Justicia Adhatoda (Vasaka) Leaf Extracts as Eco-Friendly Corrosion Inhibitor for Mild Steel in Potable Water

Introduction Mild steel pipes have been commonly used to supply potable water and corrosion of mild steel was one of the major problems in the supply network. The widely accepted technique to prevent the...

Ft-Ir, Ft-Raman and Computational Study of Phenylurea

Introduction Thiourea and substituted thioureas are versatile precursor units in the synthesis of many useful heterocyclic compounds1 .Theoretical study of the Hg2+ recognition by 1,3- diphenylthiourea has been reported2. More recently, interest has been...

Deterioration in Thermally Oxidized Mustard Oil: A Spectroscopic Investigation and Toxicological Impact on Selected Rat Tissues

Introduction Mass of population in India consumes a verity of edible oil in large amount (mustard oil, Ground nut oil, Soybean oil, etc.) edible oil are used to increase the palatability and to enhance...

Vibrational Spectroscopic Studies of 4-Chloro-3-Methylphenol

Introduction Phenol and its derivatives is the basic structural unit in a wide variety of synthetic organic compounds. They also add odour to drinking and food processing water1 and have mutagenic and carcinogenic effects2....

A Mechanistic Approach on the Solvolysis of Cinnamoyl Chloride in the Presence and Absence of Mercuric Chloride Catalyst

Introduction Cinnamoyl derivatives are used to produce compounds that have shown promising antifungal, antibacterial and anticancer activity.1-2.Hence it is important to comprehend the correlations between the chemical structure, chemical reactivity, and   solvent effects of...

Synthesis, Characterisation and Structural Studies of Complexes containing Different Schiff Bases with V (Ill) and VO (IV)

Preparation and Structural Studies of Schiff-bases and their Complexes Derived from Bio-potent Metals

Introduction Transition metal ions are essential to many biological systems in nature(1). Metal ions are involved in a large number of chemical reactions by virtue of their ability to coordinate to simple or polymeric ...

Ft-Ir, Ft-Raman and Quantum Chemical Calculations of 1-Phenylpyrrole

Introduction Substituted pyrroles represent an important class of five membered heterocycles that are the structural moieties found in several natural products and in therapeutically active compounds including fungicides1-5, antibiotics6-8, cholesterol reducing agents9 and antitumor...

Synthesis, Characterisation and Antimicrobial Screening of Co(II), Mn(II) Ni(II), Cu(II) and Zn(II) Complexes of Schiff Base Ligand

Introduction Schiff bases derived from aromatic amines and aromatic aldehydes have a wide variety of applications in many fields eg., biological, inorganic and analytical chemistry.1-5 They are known to exhibit potent antibacterial, anticonvulsant and...

Synthesis and Characterization of Copper Complexes of A Schiff Base Derived from 1H – Indole 2,3 Dione

Introduction Although there is a wealth of information concerning transition metal complexes with isatin schiff bases, only few investigations have appeared in the literature to describe the metal complexes of schiff bases derived from...

Polymorphisms in DNA Sequence and Personalized Alternative Herbal Drugs

Introduction Herbal medicines are a part of traditional Chinese medicine (TCM);  Ayurveda, and other healthcare systems such as homeopathy. Herbal drugs are considered as less potent than prescribed medicines. The latter usually contain one...

Study of Photochemistry Without Light of Substituted Benzylidine Acenaphthenones

Introduction An intriguing and potentially useful development of the mechanistic studies on chemiluminescence has been the realization that thermal decomposition of highly strained molecules provides, a useful source of excited state compounds without the...

Preparation of Calcium ion Selective Electrode using Calcium Lactate Enzyme as an Electro Active Material

Introduction Calcium and calcium salts are very important minerals used in food industry. Different calcium salts have been studied for decay prevention, sanitation and nutritional enrichment of fresh fruits and vegetables. Calcium lactate, calcium...

FT-IR, FT-Raman and Computational Study of P-Acetylbenzonitrile

Introduction The benzonitrile moiety is a relevant polar group in molecules present in calamitic and linear and nonlinear optical materials1-4. Several molecular properties, such dipole moment, polarizability (dynamic and static), polarizability anisotropies, and nonlinear...

A Facile and Green Synthesis of “5-(3-Methyl-7-Substituted-4h-1, 4-Benzothiazin-2-Yl)-4-Aryl-4h-1, 2, 4-Triazole-3-Thiols” under Ultrasound Irradiation

Introduction                                                                 1, 4-Benzothiazine nucleus is found in various drugs, having broad biological spectrum of activities such as anti parasitic, antibacterial, antiviral, antioxidant, anti- inflammatory, anti-hypertensive, anti-anginal drug, antidepressant and anti-tubercular etc. 1-4 The triazole...

A Theoretical Approach to the Study of Some Plant Extracts as Green Corrosion Inhibitor for Mild Steel in Hcl Solution

Introduction Inhibitors are added to many systems, namely, cooling systems, refinery units, chemicals, oil and gas production units, boiler, and so forth. Most of the effective inhibitors are used to contain heteroatom such as...

Spectroscopic and Biocidal Study of Co(Ii), Cu(Ii) and Ni(Ii) Chelates of Nitrogen and Sulphur Containing Schiff Base Derived from 6-Methyl-2-Phenyl-4h-Chromen-4-One

Introduction Schiff bases have the ability to act as coordinating ligands and the polynuclear complexes derived from Schiff bases find variety of applications in analytical and biological systems1-12. Schiff base complexes of transition metals...

Extractive Spectrophotometric Determination of Nicergoline Through Ion-Pair Complexation Reaction

Introduction Nicergoline (Ergoline-8-methanol,10-methoxy-1,6-dimethyl-,8-(5-bromo-3-pyridinecarboxylate) is an ergot derivative used to treat cognitive, affective behavioural disorders of older people1 (Fig. 1). It has been used to treat symptoms of mental deterioration associated with cerebrovascular insufficiency and...

2, 4-Dihydroxy-5-Bromo-Alpha-Phenylacetophenone Thiosemicarbazone (Dhb-&-Pat) as Analytical Reagent: Studies on Cu(Ii) Chelate

Introduction The thiosemicarbazone of aldehydes and ketones are found to be better chelating agents and they have been exploited to the maximum extent by many workers (1-6). Many organic reagents like o-hydroxy oximes, oximes,...

Synthesis and Evaluation of Some New Pyrazoline Derivatives as Antimicrobial Agents

Introduction Heterocyclic nitrogenous compounds and their fused analogues represent an important class of heterocyclic compounds. They exist in numerous natural products, display a wide range of biological and pharmaceutical activities. Pyrazolines are well known...

Reactivity of alpha-Hydroxy Acids Towards Piperidinium Chlorochromate Oxidation

Introduction A great variety of new chromium(VI) oxidant together with special reaction conditions have been developed for the chemospecific, regiospecific and stereospecific oxidative generation of functional groups in highly sensitive systems. Recently some neutral...

Racemisation of (1R, 6S)- 8-Benzyl-7,9-Dioxo-2,8-Diazabicyclo[4.3.0]Nonane using Halogenated Solvent in Basic Medium

Introduction Fluoroquinolones are well tolerated drugs and amongst them the fourth generation fluoroquinolones act at DNA gyrase and topoisomerase II and IV1. One of the widely used fourth generation fluoroquinolone is moxifloxacin (Figure 1)....

Simple and Validated Ultraviolet Spectrophotometric Method for the Estimation of Febuxostat in Bulk and Pharmaceutical Dosage forms

Introduction The Febuxostat chemically is 2-[3-cyano-4-(2-methylpropoxy) phenyl]-4-methylthiazole-5-carboxylic acid 1 (Fig. 1) with a molecular weight of 316.38. The molecular formula is C16H16N2O3S.  Tablets available in the local market for oral use contain the active...

Geochemical Characteristics of Heavy Metals Concentration in Sediments of Quiberon Bay Waters, South Brittany, France

Introduction Marine sediments, including materials originating from the terrestrial and land inputs, as well as atmospheric deposition and autogenetic matter from ocean itself, preserve a continuous record of regional and global environmental changes, which...

Thermodynamics of Micellization of Nonionic Surfactant Triton X-100 in Presence of Additive Poly-N-Vinyl- Pyrrolidone using Clouding Phenomenon

Introduction The clouding of ionic/nonionic surfactants and polymers alone and mixture has been studied by several research workers.1-4 The physico chemical studies of polymer surfactant solution have created much interest regarding their industrial importance....

Effect of Nano CaCo3 as A filler and Linseed oil as an Extender on the Cure and Mechanical Properties of Natural Rubber Vulcanizates

Introduction Polymer composites have mechanical and heat resistance properties superior to pristine polymers, but the improvements are achieved at the expense of increased component weight, due to the higher loading of the filler required....

Modern Method for the Preparation of Some Metal Oxides in the form of Nanometric Feature using Schiff Base Complexes as Precursors: Synthesis, Characterization and Antibacterial Properties

Eco Friendly Procedure for Synthesis of Styrylpyrazoles under Solvent Free Conditions using Microwave Irradiations

Introduction In recent years the solvent free organic reactions assisted by microwaves have gained special attention7,8. The use of microwave irradiations in organic synthesis can increase the purity of resulting products, enhance the chemical...

Quantum Chemical and Spectroscopic (Ft-Ir, Ft-Raman) Study, first order Hyperpolarizability, Nbo, Analysis Homo and Lumo Analysis of Selegiline by Abinitio Hf and Dft Method

Mer-R,S-[Znl2](NO3)2, New Zinc Complex with N-(2-Aminoethyl)-1,3-Propanediamine: Spectral and Structural Study

Introduction N-(2-Aminoethyl)-1,3-propanediamine (aepn) is a rather common tridentate amine ligand. It usually forms three coordination bonds with the same central atom1 and only rarely aepn adopts bridging function2. In the past few years we...

Potentiometric and Thermodynamic Studies of Some Metal Complexes With Carboxy Methyl Mercapto Succinic Acid

Introduction Mercapto compounds have several application in biological, pharmaceutical and other chemical fields and are well known to form complexes with various metals. Gupta and coworker1-3 have carried out significant investigation on the electrochemical...

Stigmasterol-3-O-Β-D-Arabinopyranosyl(1®4)-O-Β-D-Glucopyranoside from the Roots of Limonia Crenulata (Roxb.)

Introduction The plant Limonia crenulata (Roxb)1 is commonly know as Beli in hindi and belongs to Natural-order Rutaceae It occurs in Western and Southern India, Punjab, N.W. Himalay, Shimla, Kumaon, Bihar, Bengal and Assam....

Chemical Composition of Volatile oil from Ferula Gummosa using Hydrodistillation Profile

Introduction Ferula gummosa Boiss. (Apiaceae) is a perennial plant native to central Asia, growing in the northern and western parts of Iran and blooms once in its several years’ life span [1]. Nomads of...

New Polymeric Hydrogel Formulations Based on Poly(Vinyl Alcohol) for the Controlled Release of Bovine Serum Albumin

Introduction Poly(vinyl alcohol) (PVA) is a hydrophilic polymer which is of special interest for the application in medicine owing to its excellent biocompatibility. PVA is one of the most ancient polymers and at the...

Environmentally Relevant Supramolecular Metal Coordination Polymers Derived from 5-(3-Pyridyl)- 1,3,4-Oxadiazole-2-Thiole and Imidazole

An Efficient Oxidation of 1,4-Dihydropyridines by Hydrogen Peroxide in the Presence of Copper(II) Chlorideat at Room Temperature

Introduction For the first time 1,4-dihydropyridine synthesized by Hantzsch about one century ago. 1,4-Dihydropyridine ring is the common feature for various pharmacological activities such as antitumours [1], antivirals  [2], calcium  antagonists [3], antidiabetics [4],...

Enantion Selective Synthesis of Chairal Alfa Amino Acids by Phase Transfer Catalysts

Introduction Amino Acids are as base the units of lipids & proteins formations which they are used to make medicine. Relocating Amino acids molecules on chemical’s protein chains will produces new productions with new...

Spectrophotometric Method for the Estimation of Cilnidipine in Bulk and Pharmaceutical Dosage forms

Introduction Cilnidipine is chemically, 1,4- Dihydro- 2,6-dimethyl- 4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid 2-methoxyethyl(2E)-3-phenyl-propenyl ester. It Cilnidipine is a dual blocker of L-type voltage-gated calcium channels in vascular smooth muscle and N-type calcium channels in sympathetic nerve terminals...

Geometrical Aspects of Trinuclear Tetra-µ-Chloro-Cadmium Complex with 5-Methyl-4H-1,2,4-Triazole-3,4-Diamine

Introduction Amongst five-membered ring systems available, the presence of the three nitrogens in triazoles provides an interesting class of compounds. Triazoles in particular, substituted-1,2,4-triazole are among various heterocycles that have received the most attention...

Synthesis of 1, 4-Dihydropyridine Derivatives using Fe [(L)proline]2 as Catalyst

Introduction Chemical dihdropyridins reported by arthur hantzsch from 1882 years, he compounded ᵝ-ketoester, aldehyde and ammohia that lead to forms of 1¡4-dihidropyridines where as reported   many advantages of 1¡4-dihydropiridin ,and  at  this time identify...

A Rapid Test to Evaluate Eutrophication in Polluted Rivers

Introduction Eutrophication is either caused by human indiscriminate disposal of waste into rivers or natural means(Harper, 1992). This waste contains substances such as nitrates, phosphates, fertilisers or sewage.  Eutrophication was identified as a major...

Chemical Treatment, Characterization and Electrical Properties of Utilization Biowaste Hydroxyapatite Nanocrystalline

Aromatization of 1,4-Dihydropyridines by Hydrogen Peroxide in the Presence of Nano-Fe2O3 at Room Temperature

Introduction Chemistry of 1,4-dihydropyridine in 1882 with Arthur Hantzsch reports the ᵝ-keto ester, aldehydes and ammonia can be combined to form 1,4-Dihydropyridine is was developed. 1, 4-Dihydropyridine ring is the common feature for various...

Binuclear Copper(I) Complex Constructed by two End-to-End, µ-1,3-Azide bridges, [Cu2(PPh3)4(µ-N3)2]

Introduction The azide group (N3−) is a versatile bridging agent. It can bond to metal centers in several ways, as a terminal ligand via one nitrogen donor, as a bridge in the μ-1,1 (end-on,...

Synthesis and Characterization of Novel Amphiphilic Block Copolymer Poly(4-Vinyl Benzene Chloride)-B-Poly(Ethylene Oxide)

Introduction Amphiphilic block copolymers consist of both hydrophobic and hydrophilic chain segments combined in a single macromolecule and are typically found to aggregate and adsorb at surfaces, similar to low molecular weight surfactants 1....

Cu [(L)Proline]2 As A Novel Catalyst For Synthesis of 1, 4-Dihydropyridines

Introduction  1, 4-Dihydropyridine ring is the common feature for various pharmacological activities such as antitumours1, antivirals2, calcium antagonists3, antidiabetics4, and antagonists5. Recently a number of articles have published on the synthesis of 1, 4-dihydropyridines6-12....

Supercritical Fluid Extraction (SFE) of Malaysian Wild Ginger Zingiber puberulum Inflorescence

Introduction Malaysian natural product plants have been studied extensively. These include medicinal plant species from Andrographis1,2,3,4, Musa5, Plumeria6,7, Citrus8,9, Cymbopogon10, Garcinia11,12, Artocarpus13, Kaempferia14   and Alpinia15.  Besides medicinal plants, fish products particularly ω-fatty acids have...

Quantitative Structure Property Relationships Study of Mobility of Some Benzoaromatic Carboxylate Derivatives by Partial Least Squares and Least-Square Support Vector Machine

Introduction Separation selectivity in capillary zone electrophoresis is determined by the relative difference in the total ionic mobility of the separands. In capillary zone electrophoresis with electroosmotic flow, this total mobility consequently consists of...

Distribution of Total Petrogenic Hydrocarbon in Dungun River Basin, Malaysia

Introduction Hydrocarbons are organic compounds derived from natural or anthropogenic sources. According to Lopez and Villaizan1, only small amounts of natural hydrocarbons are present in the environment that has originated from geochemical and biosynthetic...

Can BOD5 be Estimated Without any Dilution and Manometric Methods?

Introduction In water quality analysis, the biochemical oxygen demand (BOD) is one of the recommended tests for polluted river systems and wastewaters. BOD gives the qualitative and quantitative concept of the status of organic...

A DFT Study of Solvation Effects on Tautomerism of 6-oxo Purine by Polarisable Continuum Method (PCM)

Introduction Tautomerism interconversions 1,2. have been investigated by chemists during last decades. Recently, study of tautomerism received renewed attention due to its importance on the determination of compounds properties and their area of applications....

Chemical Compositions and Physico-chemical Properties of Three Varieties Essential oils of Cymbopogon giganteus Growing to the Spontaneous State in Benin

Introduction The study of aromatic plants is still of current events considering the fact that the bioactive compounds of their essential oils focus in recent times,and effectively, theattention of researchersin the world ofmodern medicine....

Theoretical Survey on Tautomerism of Thioguanine Tautomers by Polarisable Continuum Method (PCM)

Introduction 6-Thioguanine (SG) is a known anti-cancer agent that is readily incorporated in place of guanine during DNA replication. The incorporation of SG nucleotides into DNA and RNA by polymerases can lead to cell...

Geometrical Study of a New Cobalt(III) Complex, fac-[Co(HEAC)2 ]ClO4 , Containing Eight Chiral Centers with Mixed Donor (NN’O) Ligand

Introduction The synthesis of β-amino alcohols is of current interest as they are important sub-units commonly used in the synthesis of biologically active natural and synthetic products, pharmaceuticals, synthetic amino acids and pesticides1−2 and...

Electrochemical Behavior of Silver in Sodium Sulphate Solution during Anodic Polarization Revisited

Introduction The process of formation of oxides on metals and alloys constantly causes the interest of researchers. Oxide accumulation on an electrode surface in anodic dissolution or corrosion usually results in revolutionary changes in...

Nitrogen Removal from an Aerobically Digested Domestic Wastewater using Anoxic/Oxic (A/O) Reactor Packed with Non-woven Filter Materials

Introduction Over the last two decades, rapid population growth, booming economic  growth, low wastewater treatment rate and illegal discharge of domestic and industrial wastewater, and non-point pollution sources have resulted in severe water quality...

Design and Synthesis of N-(2-{[(2-Hydroxy-naphtalen-1-yl)- phenyl-methyl]-amino}-ethyl)-3,4-dinitro-benzamide

Introduction There are several methods reported for synthesis of aromatic-condensed derivatives; for example, the synthesis of naphtyl ketone by the reaction of o-alkynylbenzaldehydes with alkynes using AuCl3 as catalyst1. Other reports indicate the tandem...

Effect of Drying on the Synthesis and Characterization of MoVTeNbOx Mixed Metal Oxide Catalysts Prepared by Reflux

Introduction The partial oxidation of abundant and much cheaper alkanes to highly value oxygenates can bring huge economic incentives to industries and end users [1], one of which is the partial oxidation of propane...

Computational Modeling and Nano-Synthesis of Graphene-Graphite Mixtures for Organic Pollutant Capture from Industrial Water-Drains

Introduction Carbaryl (1-naphthyl methylcarbamate) is a chemical in the carbamate family used chiefly as an insecticide. It is a white crystalline solid commonly sold under the brand name Sevin, a trademark of the Bayer...