Abstract

Microwave Assisted Synthesis of some Ln(III) Chloride Complexes from 4-Formyl Antipyrine Schiff Base :Structural Characterization and Antimicrobial Evaluation

Jincy Ennakkathara Muraleedharan^1*and Kaladharan Perumpaparampil Viswanathan²

DOI : http://dx.doi.org/10.13005/ojc/410130

Abstract:

The lanthanide complexes [La(L₁)₂(Cl)₂]Cl·4H₂O, [Sm(L₁)₂(Cl)₂]Cl·4H₂O, [Eu(L₁)₂(Cl)₂]Cl·4H₂O and [Dy(L₁)₂(Cl)₂]Cl·4H₂O were prepared by reaction between the antipyrine schiff base L₁ and some lanthanide chloride salts through microwave irradiation as a green and efficient method. The lanthanide complexes were characterised based on elemental analysis, molar conductance, FTIR, UV-visible & ¹H NMR spectroscopy, along with magnetic susceptibility and thermogravimetric analysis. The antimicrobial efficacy of the synthesised compounds were assessed with bacteria-E. coli, B. subtilis, A. hydrophila, K. pneumoniae, V. cholerae, and S. aureus, as well as fungi like A.fumigatus , A.flavus and C.albicans. Majority of the complexes were discovered to have potential actions against the tested harmful microorganisms.