Abstract

Sanjay P. Ramteke

DOI : http://dx.doi.org/10.13005/ojc/410134

This work is to find out the wide interactions of Tramadol molecules in ethanol at the different thermal environment, this research investigates the impact of temperature variations on the thermo-acoustic properties of tramadol drug in alcoholic solutions. The assessment and evaluation of molecular exchange interaction of alcoholic media and Tramadol drug at varied temperature have been observed under the ultrasonic mode within the range of frequency i.e. 2 MHz. The objective is to gain insights into molecular interactions and structural changes within the system by examining acoustic and thermal parameters. The peculiar deviation of these physical parameters confirms the structural change in the experimental solution so it is an appreciable sense shows the molecular interactions. Objective of study is crucial for understanding the potential effects of temperature on drug stability, solubility, and bioavailability, as well as the influence of alcohol on these properties. The findings of this research could have significant implications for drug formulation, storage, and administration, particularly in scenarios involving alcohol consumption.

Alcohol; Compressibility; Impedance; Thermo acoustic parameters; Tramadol; Ultrasonic velocity

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