ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Abstract

Synthesis, Characterisation, Biological Activities  of Transition Metal Complexes Derived from Alloxan

Padma Priya Gopalakrishnan1,2*and Girija Chamarahalli Ramakrishna Iyer3

DOI : http://dx.doi.org/10.13005/ojc/410131


Abstract:

Schiff-bases have acquired attention because of their flexible structural design and wide range of uses. In order to enhance the biological component of d block elements, our current study has been conducted to synthesize a variety of Schiff-base complexes. A weakly basic molecule results from the condensation of a keto or an aldehyde group [C=O] with an amine or amino compound. Designing novel therapeutic medications is made possible by medicinal inorganic chemists in a number of ways. This is due to the wide variety of coordination number and geometries, various redox states, thermodynamic properties, kinetic properties, and distinctive properties of the metal ions being available. Alloxan- 2,4,5,6[1H,3H] pyrimidinetetrone is a heterocyclic compound with high biological and physiological effect on living organisms A potential path toward the development of new materials with a wide range of applications is offered by organometallic complexes. A foundation for developing drugs that may be applied in a variety of settings is provided by the electrical changes that take place between metal-ligand complexes. Schiff base ligand and its metal acetyl acetonate complex is synthesised in an ecofriendly way using microwave assisted reaction.

Keywords:

Alloxan orthophenylenediimine; acetyl acetonate complexes; Antibacterial; Docking; HNMR; IR; TGA; UV

[ View HTML Full Text]

Back to TOC