Abstract

Mohammad Abdul Alim¹, Md. Abul Bashar², Partha Sarathi Roy¹, Md. Nuruzzaman Khan³, Pijush Kanti Roy⁴, Md. Siddik Ali⁵, Md. Rezaul Haque Ansary⁵ and Md. Motahar Hossain^5*

DOI : http://dx.doi.org/10.13005/ojc/400528

Together, ortho (o)-phenyldiamine and para (p)-hydroxy benzaldehyde generate a Schiff base (SB). In order to make transition metal complexes of  Ni²⁺, Cu²⁺, Co²⁺ and Cd²⁺ ions, this Schiff base (SB) was employed as a ligand of choice. The generated transition metal complexes' chemical structure is examined using a variety of physical methods, such as fundamental analysis, conductivity (molar), susceptibility (magnetic), spectroscopy (IR), and electronic spin spectroscopy. According to the elemental data analysis, a 1:2 [M:2L] complex of the formula,  is produced ( M²⁺ = Ni²⁺, Cu²⁺, Co²⁺ and Cd²⁺  ions and L= Schiff base). All of the complexes were shown to be electrolytic in nature, as demonstrated by the molar conductance (conductivity) experiment. The ¹H NMR and infrared (IR) spectral studies were utilized to fix the Schiff base binding sites that the transition metal ions are attached to. The anticipated coordination geometry and magnetic characteristics, such as the magnet with paramagnetic or diamagentic of the complexes were validated by the magnetic susceptibility tests and electronic spectral data. While the Cd²⁺ ion creates tetrahedral structure with low spin, the Ni²⁺and Cu²⁺, Co²⁺ ions yield high spin tetrahedra geometry. Comparing the obtained results with common antibiotics as kanamycin and ampicillin, the Cu²⁺ and Ni²⁺complexes showed high activity, while the Co²⁺ and Cd²⁺ complexes showed week and occasionally moderate antimicrobial activity. The complex compounds of Schiff base showed more activity towards gram position and gram negative bacteria as compared to its Schiff base. This idea can be improved upon with more adjustments and used in the pharmaceutical or medical industries.

Anti-microbial action; Metal Complex; Schiff base; Spectral investigation

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