ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Antibacterial Effects of Mo(VI) Macrocyclic Compounds

Shikha Katiyar1, Siddharam1, Devendra Pratap Rao1* and Shiv Govind Prasad2

DOI : http://dx.doi.org/10.13005/ojc/400518


Abstract:

Preparing a monomeric [MoO2(SL)] containing a Schiff base was achieved by condensing furil with 3-bromo-5-(trifluoromethyl) benzene-1,2-diamine, along with preparing 4 different compounds containing [MoO2(MSL). A study of the interaction between 1,3-diketones and [MoO2(SL)] is presented in this paper. As part of the study, UV-Vis, magnetic, IR, NMR, and thermal characterization were carried out on five MoO2(VI) compounds. The coordination number of Mo will be six. The molybdenum octahedral geometry in these compounds consists of 4 N- and 2 O-atoms. When tested against S. aureus and S. typhi, there was moderate activity in all compounds synthesized. It is based on the chelation hypothesis that antibacterial tasks progress.

Keywords:

Antibacterial Activity; β-diketones; Chelation Presumption; Furil; Molybdenum(VI); Macrocyclic Compounds; Schiff base

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