Abstract
Synthesis and Characterization of Some Fluorinated 1, 5 - Benzothiazepines and Pyrazolines
S. G. Jagadhani*, S. G. Kundlikar and B. K. Karale
DOI : http://dx.doi.org/10.13005/ojc/310177
Abstract:
4-Bromo-2-fluorobenzaldehyde 1 when treated with substituted hydroxy acetophenones 2 yields chalcones 3. These chalcones were refluxed with 2-aminothiophenol gave “2-[2-(4-bromo-2-fluorophenyl)-2,3-dihydro-1,5-benzothiazepin-4-yl]phenol” 4 and when treated with hydrazine hydrate gave the compound “2-[5-(4-bromo-2-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]phenol” 5. The structures of compounds have been established on the basis of spectral data.
Keywords:Fluorinated Chalcones; Benzothiazepines; Pyrazolines
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