Abstract

V. H. Rajurkar*,  V. N. Kamble

DOI : http://dx.doi.org/10.13005/ojc/310171

Reaction between 2,3-Butanedione 3-monoxime, 3-aminophenol and some hydrated metal salts of  Mn^II and Fe^II give complexes of the type [ML₂2(H₂O)]. The ligand and the complexes were characterized by elemental analysis, magnetic susceptibility measurements, spectral (U.V.Vis., I.R., ¹H N.M.R.) analysis and X-ray powder diffraction studies. Spectral studies indicate bidentate nature of the ligand and coordination occurs through oxime oxygen after deprotonation and nitrogen of azomethine. The spectral and magnetic studies suggest octahedral geometries for both the complexes. A triclinic system was proposed by X-ray powder diffraction study of Schiff base and metal complex. Anti-bacterial and anti-fungal activity have been studied using the agar well diffusion method and ditch diffusion method. The activity data shows that the metal complexes are more potent antibacterial and antifungal than the parent Schiff base ligand.

Schiff base; transition metal complexes; Triclinic system; Biological activity

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