Abstract

V. Priya Roseline
and V Priya

DOI : http://dx.doi.org/10.13005/ojc/390218

The nano sized copper oxide material (CuONPs) were prepared by the greener way and an approach functionalized by polymer using Sarcostemma acidum stem extracts. The in-vitro anti-diabetic activity was studied through the α-glucosidase and α-amylase inhibitory methods were demonstrated in Sarcostemma acidum stem, biological synthesized CuONPs and polymerized CuONPs. The percentage inhibition at 100 μg/ml, 200 μg/ml, 300 μg/ml, 400 μg/ml and 500μg/ml concentrations of Sarcostemma acidum stem, biological synthesized and polymerised CuONPs showed dose dependent inhibition in α-amylase and α-glucosidase. Throughout the studies, polymerized CuONPs showed highest inhibition of α-amylase and α-glucosidase as compared with green synthesis.

α-amylase; α- glucosidase; Antidiabetic activity; Copper oxide nanoparticles; Sarcostemma acidum

[ View HTML Full Text]