Abstract
Novel Substituted Indazoles towards Potential Antimicrobial Agents
Jaganmohana Rao Saketi1, S N Murthy Boddapati1,2, Raghuram M3, Geetha Bhavani Koduru4
and Haribabu Bollikolla1*
DOI : http://dx.doi.org/10.13005/ojc/370234
Abstract:
The in vitroantimicrobial properties of a series of N-methyl-3-aryl indazoles (5a-5j) were screened. In this present work, we describe our efforts towards the development of potent antimicrobial activity of synthesized indazole derivatives. The antimicrobial activities of the prepared compounds were investigated against four bacterial strains: Xanthomonascampestris, Escherichia coli, Bacillus cereus, Bacillus megaterium, and a fungal strain Candida albicans. The biological evaluation studies of these indazole derivatives revealed that some of these tested compounds have shown moderate to goodin vitroantimicrobial activities.
Keywords:Antimicrobial Activity; Indazole; Well Diffusion
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