Abstract

Nursabah Sarıkavaklı^1*, Emrah Koç¹ , Meshari M.H. Aljohani² and Syed Khalid Mustafa²

DOI : http://dx.doi.org/10.13005/ojc/360626

A modest attempt has been made for the synthesis of hydrazoneoxime ligands bearing pyrazolone group (1-4) and their successive metal complexes such as: 1(a-c), 2(a-c), 3(a-c) and 4(a-c). The precursor (1Z,2E)-2-(hydroxyimino) ethanehydroximohydrazide (GH2) was obtained throughcoupling of (1Z,2E)-N-hydroxy-2-(hydroxyimino) ethanimidoyl chlorideand hydrazinium hydroxideto generate hydrazonoxime compounds bearing the pyrazolone group. The ligands (1-4) were were reactedwith MX2.nH2O, where M = Co(II), Ni(II), and Cu(II) to obtain the successive metal coordinated compounds into good yields. Theligands and their metal complexeswere investigated byusing 1HNMR, 13CNMR, FT-IR, elemental analysis, and magnetic susceptibility measuremented.Tautomerism in the ligands is investigated spectroscopically and biological activities are evaluated as well. Finally, the findings of present study were found within good egreement with other worker.

Biological Activities; Hydrazoneoxime; Metal complexes; Pyrazolone; Spectral studies; Tautomerism

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