Abstract

Samiran Halder¹ and Arup Datta^2*

DOI : http://dx.doi.org/10.13005/ojc/360623

One pot highly efficient chemoselective N-arylmethyl benzimidazole has been prepared by using catalyst TiCp2Cl2 in tetrahydrofuran solvent smoothly. This method is very much effective for the condensation between different aldehydes and various ortho-phenylenediamine to synthesize N-substituted benzimidazole. Clean reaction procedure, quick reaction, easy purification and high yield of the product are some advantages of this protocol. All the target molecules were identified by spectroscopic analysis and also verified melting points from literature value.

Bis(cyclopentadienyl) titanium(IV) dichloride; Chemoselective synthesis: N-arylmethyl Benzimidazole; Ortho-Phenylenediamines

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