Abstract

Larcy Marie O. Pagbilao^1,2, Danilet Vi M. Mendoza^2*, Marilene C. Hipolito², Jocelyn P. Gabriel² and Mario M. Abesamis. Jr.²

DOI : http://dx.doi.org/10.13005/ojc/360319

Wound dressing is a vital component of wound infection management specially by immunocompromised patients due to accidents that caused injuries. Biodegradable hydrogel-based wound dressings are being developed to acquire the advantage of high swelling capacity and being environment friendly at the same time. The study involves development of hydrogels using solution casting method with different ratio of rice bran starch. Mechanical properties such as tensile strength and swelling capacity were determined. The hydrogel developed with 7% starch emerged with comparable tensile strength and swelling capacity with the available wound dressing in the market. FT-IR spectra confirmed the crosslinking of PVA and starch while SEM images revealed that the hydrogel is not porous. Drug loading capacity of the hydrogel was determined to be 83.48% with PBS which is higher than with water. Results suggest that the developed hydrogel has great potential for wound dressing application with the advantage of being biodegradable.

Biodegradable Hydrogel; Hydrogel; Rice Bran; Wound Dressing

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