Abstract

Soheila Ghaderi and Davood Setamdideh^*

DOI : http://dx.doi.org/10.13005/ojc/300452

NaBH₄ (1.25 equivalents) & NaNO₃ (3 equivalents) reduce a variety of aldehydes in the presence of ketones to their corresponding alcohols. Also, regioselectivity and exclusive 1,2-reduction enals to their corresponding allylic alcohols in high to excellent yields was achieved successfully with this reducing system. The reduction reactions were carried out in water as green solvent in high to excellent yields of the products. A nitrate-borane complex [H₃B-NO₃]Na is possibly the active reductant in the reaction mixture.

NaBH4; Selective Reduction; Aldehydes; NaNO3

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