Abstract
Synthesis of Oxadiazole Derivative of Pentacyclic Triterpenoid and Its Biological Activity
Mohammed Golam Rasul*
DOI : http://dx.doi.org/10.13005/ojc/350331
Abstract:
Triterpenoid betunilic acid is extracted from outer bark of Biscofia javanica blume from Darjeeling hilly region and carried out transformative reaction to introduce oxadiazole moiety to ring A of the triterpenoid which was identified as 28-carbomethoxy lupan (2,3-c)-1′,2′,5′-oxadiazole. The derivative obtained has been selected for its antibacterial and fungicidal activity at different concentrations with respect to the parent compound. The structures of this compound were established based on spectroscopic (UV, IR, NMR) analysis.
Keywords:Biological Activity; Extraction; Phytotoxicity; Transformative Reaction; Triterpenoid
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