Abstract

Muhammad Saleh Salga¹, Ibrahim Sada¹ and Abdullahi Mustapha²

DOI : http://dx.doi.org/10.13005/ojc/300410

Herein we report the synthesis, characterization and antioxidant activity of the Schiff base ligands (E)-4-bromo-2-((2-piperazine-1-yl)ethylimino) methylphenol and 2,2’-(1E,1E’)-cyclohexane-1,2-diylbis(azan-1-yl-1-ylidene))bismethan-1-yl-1-ylidene)bis (4-bromophenol) and their complexes of copper (II) ion. Antioxidant activities of the copper complexes were studied by ferric reducing antioxidant power (FRAP) assay according to the procedure reported by Benzie and Strain¹ which considered the reduction of ferric tripyridyl triazine complex to a ferrous complex at low pH by monitoring the change in absorption at 593 nm. The overall results showed an increased in antioxidant activity with the increase in steric crowd. Similarly, the ligands show high activity than the complexes.

Synthesis; characterization; antioxidant activity

[ View HTML Full Text]