ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis of New Organoselenium Compounds Containing Nucleosides as Antioxidant

Laila M. Break1, Mahmoud A. Mohamed1,2 and Shams H. Abdel-Hafez1,3

DOI : http://dx.doi.org/10.13005/ojc/300423


Abstract:

Selenium containing nucleosides derived from some heterocyclic moieties such as Pyridineselenol, and pyridazineselenol is described herein. Ribosylation of selenol compounds were prepared in good yield by silyation of selenol derivatives with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose followed by debenzoylation to afford the corresponding free N-nucleosides b and a-1-(2,3,5-trihydroxy-

Keywords:

1-O-Acetyl-2,3,5-trihydroxy-β-D-ribofuranose; Nucleosides; Selenium ; Pyridineselenol; pyridazineselenol; antioxidants

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