Abstract

Febri Odel Nitbani¹, Jumina², Dwi Siswanta³, Eti Nurwening Sholikhah⁴ and Dhina Fitriastuti⁴

DOI : http://dx.doi.org/10.13005/ojc/340233

An improvement of method for synthesizing 1-monolaurin from lauric acid and glycerol has been done. The reaction was carried on mol ratio between lauric acid and glycerol 1:1 at 130°C for 6 h with variation of pTSA catalyst of 2.5%, 5%, 7.5% (w/w of lauric acid).The purification of 1-monolaurin was conducted only by extracting with hydroalcoholic solution. The product of 1-monolaurin was obtained as a white solid with 100% of purity from variation of 2.5% and 5% of pTSA catalyst with 43.54% and 27.89% yield, respectively. 1-Monolaurin could inhibit the growth of S. aureus and E. coli bacteria at 500 µg/mL of concentration.

Lauric Acid; Glycerol; Monolaurin; Antibacteria

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