Abstract

S. H. El-Zanfally, M. M. El-Enany,* S. M. Roshdy* And A. A- Moneer

A series of 2-styryl-3-aryl-4-oxo-5,6-tetramethylenethieno [ 2,3-d ] pyrimidines have been synthesized (V1-20). Condensation of 2-methyl-4-oxo-5,6-tetramethylenthieno [ 3,1 ] oxazine with certain heteroaromatic amines afforded the corresponding thienopyrimidone derivatiyes (VI1,2). Some compounds have been pharmacologically screened for their hypnotic activity.

Biologicall; Substituted; Thienopy; Rimidones

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