Abstract

Synthesis of Some new Nucleosides Derived from 2- Mercapto Benzimidazole With Expected Biological Activity

Hamada. H. Amer,^1,², Omar. M. Ali^1,³, and Ibrahim Kh. El-kafaween¹

DOI : http://dx.doi.org/10.13005/ojc/330519

Abstract:

2-mercaptobenzimidazole derivatives and their acyclic nucleosides were synthesized. The synthesized compounds were tested for their antibacterial activity against Escherichia coli, Staphylococcus aureus and S. epidermidis. Most of tested compounds showed moderate to high antibacterial activity while few compounds were found to show little or no activity against the tested microorganisms.

Keywords:

Oxadiazolines; Arylidene Derivatives; Nucleosides; Antibacterial Activity

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