Abstract

Rachaneewan Karnka¹, Preeyaporn Chaiyasat² and Amorn Chaiyasat³

DOI : http://dx.doi.org/10.13005/ojc/330529

In this work, precipitation polymerization was used to prepare uniform and stable molecular imprinting polymers (MIPs) particles without post treatment. Melamine was used as a template molecule model, while methacrylic acid, divinyl benzene (DVB) or ethylene glycol dimethacrylate (EGDMA) and acetonitrile were used as functional monomer, cross-linker and continuous phase, respectively. The polymerization was carried out in a vacuum condition at 70°C using benzoyl peroxide as an initiator. The obtained MIP particles demonstrated spherical shape with narrow particle size distribution. The particle size varied from micrometer-sized to sub-micrometer-sized depending on the initiator content. After purification, MIP particles represented high colloidal stability in aqueous medium.The binding efficiency of MIP using both cross-linkers (DVB and EGDMA) with melamine was approximately 20 mg/g MIP. The miscibility of all components where the functional monomer effectively pre-bound with the template molecules was the main factor for obtaining MIP particle with high binding efficiency.

Uniform MIP Particle; Melamine; Precipitation Polymerization; Homogeneous Nucleation

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