Abstract

Luigi Campanella¹*, Patrizia Ercole¹, Marida Lis!¹, Maria P., Sammartino¹, Mario V. Russo², Giovanni Visco¹

In the present work healthy and cancerous tissues were tested in order to observe, if any, the differences in the metabolic capacity, the metabolic pathways being often modified in the cancerous tissues. The control of the degradation of benzene due to the kidney tissue was performed by a complex procedure based on the radioactive benzene marked with 14C, then sure of the efficiency of the kidney enzymes, a simpler way was run by preparing an human kidney tissue based biosensor to be used no in the traditional way to determine the substrate but to study the efficiency of the benzene biodegradation.

radioactive; enzymes; biodegradation

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