ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

An Efficient Method For The One-Pot, Four-Component Benzaldehyde Based Synthesis of 3-Methyl-1,4-Diphenyl-7,8-Dihydro-1H-Furo[3,4-E]Pyrazolo[3,4-B]Pyridin-5(4H)-Ones Catalyzed by Alum in Environment-Friendly Media.

Sadif A. Shirvan1*,Fereydoon Khazali1, Sara Haydari Dezfuli1 And Ali Borsalani2

DOI : http://dx.doi.org/10.13005/ojc/300135


Abstract:

A mild and efficient method for the synthesis of 3-methyl-1,4- diphenyl-7,8-dihydro-1H-furo[3,4-e]pyrazolo[3,4-b]pyridin-5(4H)-one derivatives via one-pot, four-component reaction of aromatic aldehydes, tetronic acid, 3-aminobut-2-enenitrile,  and phenylhydrazine is described using Alum as catalyst. The features of this procedure are mild reaction conditions, excellent yields, short reaction time, and operational simplicity.

Keywords:

Alum; Multicomponent Reactions (MCRs); Ionic liquids; benzaldehyde

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