Abstract

Mohammed Rais Khan and Sahdev

A new Mannich base,N-(morpholinobenzyl)benzamide (MBB),formed by the condensation of morpholine,benzamide and benzaldehyde and its Fe(II), Fe(III), Mn(III), Co(III), Ti(III), V(III), V(IV), MoO(V), Ru(II) and Ru(III) complexes have been Synthesized.Their probable structures have been determined on the basis of their microanalytical,IR,UV-vis ¹H NMR spectral data. All the complexes exhibit octahedral geometry. The molar conductance data suggested 1:1 electrolytic nature for all complexes except Ru(II) and Fe(II) which are non-electrolytes and V(IV) is 1:2 electrolyte. Based on these studies all the complexes have been assigned octahexzobity. The biological activities of the ligand and its metal chelates against the bacteria E.coli,Staphylococcus aureus, Klebsiella pneumonia, Salmonella typhi, Pseudomonas aeruginosa and Shigella flexnri are also reported. The complexes have higher activity than that of the free Mannich base and the control.

N-(morpholinobenzyl) benzamide; Morpholine; Benzamide and Mannich base

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