Abstract

Neti Srinivasan¹-², Vijayavitthal T. Mathad¹, Vurimindi Himabindu²

An efficient, scalable and high yielding process is developed for a neuromuscular blocking agent Rocuronium bromide 1 by studying various process parameters. The process involves simple work up and obviates column chromatography purification and usage of commercially unacceptable solvents.

Rocuronium Bromide; neuro muscular blocking agent; diepoxide; acetylation; allylation

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