ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis of Benzothiazole Derivatives and Study of Their Antifungal Activities

Sibaji Sarkar1*, T. Y. Pasha1, B. Shivakumar2 and Rajshekar Chimkode


Abstract:

Synthesis of new benzothiazole derivatives, derived from the condensation of 2-amino-7-chloro-6 fluro benzothiazole with different aroyl chloride and obtained compounds has been (substituted phenyl carboxamido) benothiazole and obtained compounds has been subjected to a substitution reaction with different amines to yield 7alkyl/aryl amino-6-fluro-2-phenyl carboxamido benzothiazoles and 7alkyl/aryl amino-6-fluro-2 (3-nitro phenyl carboxamido) benzothiazoles. The synthesized compounds were screened for antifungal activities.

Keywords:

Benzothiazole derivatives; antifungal activity

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