Abstract

Jagbir Gagoria¹, Anurag Khatkar, Sarita Khatkar, Rekha Rao², Kuldeep Singh³ and Arun Nanda⁴

A new series of (Z)-N-(substitutedphenyl)-2-(2-((4-oxo-2-thiazolidin-5-ylidine) methyl)phenoxy)acetamides (d1- 8) have been synthesized by reaction of 2-thioxo-4-thiazolidinone(a) with salicyldehyde and vanilline, which upon O-alkylation with different chloro - acetamides (c1- 4) form the final derivatives (d1- 8). The physical and spectral data of synthesized compounds are determined. The synthesized compounds have been screened for their anti-convulsant activity by MES method.

Acetamides; Anti-convulsant activity; MES method

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