Abstract

S.Imam pasha^*, Shravan kumar.A, K. Sravanthi, G. Srinika and  V. Nikhila

A simple, sensitive and economical spectrophotometric method was developed for the determination of cefixime trihydrate in pharmaceutical formulations. This method  is based on the formation of  pink colored chromogen complex by the reaction of drug with ferric chloride and 2, 2 bipyridyl, which absorbs maximally at 520 nm. Beer’s law is obeyed at a concentration range of  1-10 mcg/ml for method. This method has been successfully applied for the assay of the drug in pharmaceutical formulations.

cefixime trihydrate; ferric chloride; 2, 2 bipyridyl; Spectrophotometry

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