Abstract

Lalit Kumar*¹, Pardeep Kumar³, and Niranjan kaushik²

3-(1-Phenyl-vinyl)-1, 2, 5-trioxa-spiro undecane is synthetic derivative of Artemisinin. Artemisinin is a well known antimalarial drug from leaves of Artemisia annua find in china. Five different derivatives of 3-(1-Phenyl-vinyl)-1, 2, 5-trioxa-spiro undecane were synthesized using well standardized method. These compounds were purified by simple column chromatography and successfully analysed using H1NMR, IR and FAB-MS techniques.

1, 2, 4-trioxane; Artemisinin; NMR; IR; FAB-MS

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