Abstract

Alok K. Pareek*, P. E . Joseph and Daya S. Seth

A new class of highly efficient, convenient and rapid synthesis of fluorine substituted thio-semicarbazide derivatives containing different functional groups have been obtained by the condensation reactions of substituted phenyl-isothiocyanate with R-malon anilic acid hydrazides(1a-1l) and substituted thio-semicarbazones have also been synthesized by the condensation reactions between selected substituted aromatic aldehydes with newly synthesized substituted thio-semicarbazides(2a-2b) in the presence of glacial acetic acid. The structures of newly synthesized substituted thio-semicarbazides & substituted thio-semicarbazones have been characterized on the basis of their spectral studies viz: IR, Elemental analysis, Physical properties.

Synthesis; substituted thio-semicarbazides; substituted thio-semicarbazones; Glacial acetic acid; condensation; spectral analysis

[ View HTML Full Text]