Abstract

Safwan M. Obeidat* and Ban Al-Tayyem

In this study, three common drugs (Cipram®, Panadol extra ®, Xenical®) were investigated. The study involved analyzing the above drugs using the portable NIR spectroscopy. Ten adulterated tablets of each of the above drugs were tested along with ten genuine tablets and other ten placebo tablets which represents another adulterated source for all drugs. Chemometrical Algorithms like Principal Components Analysis (PCA) and Cluster Analysis (CA) were used to extract the useful information from the collected data. Differentiating among original and the counterfeit drugs was successfully demonstrated with no chemical pretreatment. Identifying adulteration source was also possible using the above algorithms.

Potable NIRS; Counterfeit Drugs; PCA; CA; Medicines

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