ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Biological Evaluation of N3-(4-Substituted Phenyl)-N5-Phenyl-4H-1, 2, 4-Triazole-3,5-Diamine Derivatives

Pawan K. Mishra1, Rupesh Dudhe2, Anshu Chaudhary1 and P. K. Sharma1


Abstract:

A series of some new  N3-(4-substituted phenyl)-n5-phenyl-4h-1, 2, 4-triazole-3,5-diamine derivatives (6a-f) were synthesized from different substituted aniline(1a-f) and tested for antibacterial, antifungal activities against  human pathogenic bacteria and fungi. The structure of the synthesized compounds was elucidated by IR and 1HNMR spectroscopic techniques. The antibacterial and antifungal screening of the synthesized compound were performed in-vitro by the disc diffusion method.

Keywords:

Triazole; Anti-bacterial; Anti-fungal; disc diffusion

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