Abstract
Syntheses and characterization of some 1, 2, 4-triazole derivatives as biological agents
Ram Janam Singh1* and Dharmendra Kumar Singh2
Abstract:
3-Alkyl -4-amino-4, 5-dihydro-1H-1, 2, 4-triazole-5-one (1) when condensed with di-(3-formyl phenyl)-terephthalate (2) yielded the corresponding novel di-[3-(3-alkyl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethinphenyl]-terephthalate (3). All the synthesized compounds were characterized by IR, PMR, Mass spectral data and elemental analyses. All newly synthesized compounds have been assayed for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa
Keywords:4, 5-dihydro-1H-1, 2, 4-triazole-5-one; di-(3-formyl phenyl)-terephthalate; condensation; cyclization; antibacterial activity
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