Abstract

Javad Azizian¹*, Abolghasem Shameli², Ebrahim Balali³, Mohammad Mehdei Ghanbari⁴ and Shahab Zomorodbakhsh⁵

There is a continued interest in the regioselective ring opening of oxiranes to the corresponding vicinal halohydrins. Although a variety of new and mild procedures to effect this transformation have been reported, most of them have some limitations.The ring opening of epoxides with elemental bromine and nano catalyst ZrO₂affords vicinal bromo alcohols in high yields. This new procedure occurs regioselectively under neutral and mild conditions in various aprotic solvents even when sensitive functional groups are present.

Ring opening; epoxides; regioselective; bromine; nano catalyst; alcohols

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