Abstract

M. P. Bhise¹,V. M. Raut¹, R. P. Pawar¹, G. P. Gulwade¹ and N²

3-Aroyl flavanones were allowed to react with hydrazine hydrate in dioxane containing little piperidine to give corresponding 3-(2-hydroxyphenyl)-4-aroyl-5-arylpyrazolines. Their structural assignment are based on elemental analysis, spectral data (IR, UV & NMR) and chemical properties. All these compounds were tested in vitro for their antibacterial activity by disk-diffusion method against gram positive and gram negative bacterias. In some of the compounds the results are found to be encouraging.

3-(2-Hydroxyphenyl)-4-aroyl-5-arylpyrazoline; Antimicrobial activity

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