ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Separation of thaiamine mononitrate ascorbic acid calcium-D-pantothenate, Niacinamide. pyridoxine hydrochloride and riboflavin by using propyl hydroxy b-cyclodextrin as an ion-pairing reagent

Mohammad Tawkir1* and S.A. Iqbal2


Abstract:

The present communication dipics the development of a reversed phase H.P.L C. for the simultaneous estimation of acidic and basic vitamins from solid dosage of polyvitamin and vitamin - B-complex tablets of therapeutic and prophylactic N.F.I. The seperation of vitamins was determined at 280nm. The proposed method is advantageous over reported method, the introduction of propyl hydroxy b-cyclodextrin as an ion-pairing reagent used and found to be profound effect over other ion-pairing reagent. The proposed methods are linear accurate and precise and applicable for daily quality control routine analysis

Keywords:

b-Cyclodextrin; Vitamin - B-complex; Ion-pairing reagent; separation of vitamins

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