Abstract

R. Suresh¹, M. Deepa^2*, P. Moganavally³ and P. N Sudha⁴

DOI : http://dx.doi.org/10.13005/ojc/320521

The Carboxymethyl chitosan Schiff base (CSB) derivative and its cobalt and nickel complexes (CSB-Co & CSB-Ni) have synthesized. The FTIR results showed the interaction with the amine of Carboxymethyl chitosan and aldehyde confirming the Schiff base formation. The XRD results, in comparison to CMC, displayed weaker peaks, which shows a decrease in crystalline properties and also exhibits the amorphous nature. The catalytic activity of the prepared CSB and its metal complexes were in the order, CSB > CSB-Co > CMC > CSB-Ni complex. From the DPPH studies, ALP assay and cytotoxic studies, the result proves that the prepared sample is non-toxic, biocompatible and has good antioxidant activity.

Carboxymethyl chitosan; Schiff base; biological activity; catalytic activity

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