Abstract

M. M. Radwan^1*, H.K. Abd El-Hamid¹ and Shaymaa M. Nagi²

DOI : http://dx.doi.org/10.13005/ojc/320516

Nano particles made of pure single phase Mineral trioxide [tricalcium silicate (C₃S)] and Tetracalcium phosphate (TTCP) bio ceramics were prepared via solid state reaction at high temperature. Setting times, compressive strength, pH, XRD, FTIR and scanning electron microscopy (SEM) were investigated. Cytotoxicity and antibacterial activity of both C₃S and TTCP to human gingival fibroblasts were studied. Both C₃S and TTCP compounds undergo hydration reaction when mixed with distilled water. A delayed setting time and very poor mechanical properties for TTCP were detected compared to those of C₃S phase. The nano-structure C₃S bio ceramic was found to be completely safe to BHK cellscompared with TTCP. The prepared C₃S and TTCP pastes were applied to the demineralized dentin specimens for seven days. The ultramorphology of dentin revealed that both C₃S and TTCPare successful in dentinal tubules occlusion, thus they are beneficial for dental application in the treatment of teeth hypersensitivity.

Tricalcium silicate; Tetracalcium phosphate; Dentinal tubules; Teeth hypersensitivity; Cytotoxicity

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