Abstract
One-Pot Synthesis of 3,4-Dihydropyrimidones Catalysed by Mercury(Ii) Chloride: an Improved Procedure for Biginelli Reaction
Mandaloju Neelanjana Rao and Chitneni Prasad Rao*
Abstract:
An efficient method for the Biginelli reaction of aldehydes, ethyl acetoacetate and urea employing mercuric chloride as catalyst. These improved reaction conditions allow the synthesis of a wide variety of dihydropyrimidinones in excellent yields under mild reaction conditions with simple work up procedure.
Keywords:3;4-dihydropyrimidones; Mercury (II) chloride; Biginelli reaction
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