Abstract

S. M. Hipparagi et al.,

We prepared 7-Substituted-6-fluorobenzothiazol-2-ylamine(K2) from 3-Chloro-4-fluorophenylamine. 7-substituted-6-fluorobenzothiazol-2-ylamine on treated with hydrazine hydrate to get 7-substituted-6-fluoro-benzothiazol-2-yl-hydrazine(K3) and than prepared 7-substituted-2-(3,5-dimethyl-pyrazol-1-yl)-6-fluoro-2,3-dihydrobenzothiazole(KS 1-9). Various compounds and their derivatives were prepared and confirmed by IR, NMR. Antimicrobial study shows that synthesized compounds have moderate activity.

Benzothiazole; pyrazole; antimicrobial activity

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